How do Erectile Dysfunction (ED) Drugs Work? All three ED drugs are known as PDE-5 inhibitors. When a man becomes sexually aroused a secondary chemical messenger known as cGMP causes the smooth muscles of the CC to relax. This allows blood to flow to the penis and an erection occurs. This same process works for woman leading to engorgement of the genitalia.
An enzyme known as PDE-5 breaks down cGMP which leads to a softer erection and ultimately a flaccid penis. All three ED drugs inhibit the functioning of PDE-5 and the subsequent breakdown of cGMP. That is why they are effective in treating ED.
The question of whether ED drugs simply help men who suffer from an inability to get and obtain a satisfactory erection or do they enhance the experience of even normal men is an important one as we will see latter.
A paper written by A Keith, The Economics of Viagra discusses this issue. Ms. Keith is Director, Economic Policy Analysis, in Corporate Strategic Planning and Policy for Pfizer, Inc., a major drug company and the company that introduced Viagra. The author states that clinical trials demonstrated that Viagra would not confer exaggerated powers on men who did not suffer from ED. Subsequently, she again notes that the consumer will quickly recognize that Viagra does not enhance sexual performance.
Based on everything that I have read and know this is not the case. Simple logic, the anatomy of the penis and the process by which this drug works would lead to the conclusion that the use of Viagra would result in a harder erection, increased erectile stamina and a longer period of time for the penis to become flaccid after ejaculation.
A study done in Buenos Aires, Argentina among healthy men between the ages of 18-30 years revealed that Viagra was used for better erection quality and better sexual performance. This group of healthy men are hardly in the age group that suffers from ED.
It it so commonly accepted that Viagra enhances erectile quality and male sexual performance that there is even a Robins Williams skit on the topic: