Does Peyronies Turn Into Cancer? - Cells obtained from Peyronies plaque have demonstrated a number of characteristics similar to cancer cells, such as the ability to resist a process of programmed cell death called apoptosis and to form tumors when transplanted into laboratory mice specifically bred to have no immune systems. However, according to the University of Georgia Urology Department, there has never been a case of PD that has turned into a human cancer.
Men Are Desperate - A common outcome of PD is a decrease of penile dimensions; both shortening and decreased girth. I have written to a number of pharmaceutical companies trying to convince them to test their Erectile Dysfunction (ED) drugs such as Viagra on PD men because an effective treatment would be gold mine as men would pay anything to regain their normal functioning and penile shape. Nothing better illustrates this than the following story. A number of lower socio-economic men in Doha, Qatar were convinced by non medical personnel that penile injections of cod liver oil would augment their size. Subsequently, all these men required emergency surgical intervention and were reported to have recovered from this “treatment.”
Revision Of A Clinical Trial - In a previous edition of this website, I reported on a PD clinical trial in Brazil using heat via a heat lamp, Vitamin D and possible administration of testosterone. The researcher has modified his clinical trial to apply heat via an infrared laser. This is a positive approach as laser heat is more precise and there has been a previous clinical trial in which is was reported that laser produced heat was beneficial in healing scar tissue. At this point, I do not believe there has been a prior attempt to duplicate results from the original trial. Click here and here for further information.
DO Try This At Home - The most common question I get from readers is depressingly familiar. “I have recently been diagnosed with PD, please help me, what can I do?” Here is one suggestion. This treatment is short term, no known adverse side effects, inexpensive and does not even require a doctor’s visit. And you have absolutely nothing to lose by trying it.
Add Curcumin To Your Diet
Curcumin — is a component of the Indian spice Turmeric. PD is a fibrotic disorder and Curcumin had been repeatedly shown to be an effective antifribrotic agent. In one experiment, mice who were genetically altered to spontaneously develop progressive inflammatory conditions of the liver, including fibrotic changes (scarring) had Curcumin added to their diet for a period of four and eight weeks. Researchers found that Curcumin reduced inflammation and scarring at both four and eight weeks intervals. No such delay in liver fibrosis was seen in the control group. Curcumin interferes with several chemical signaling pathways involved in the inflammatory process. In an article that appeared in the American Journal of Nephrology, 2010, it was also reported that Curumin also demonstrated antifibrotic properties for the treatment of kidney scarring.
ERECTILE DYSFUNCTION DRUGS AND PEYRONIES In previous editions of the site, I have pointed out that the common class of ED drugs known as PDE5 inhibitors such as Viagra, etc., have demonstrated antifibrotic properties in laboratory rats and may lessen the damage caused by PD in humans. I have suggested that interested readers talk to their urologists about taking these drugs during the active phase of their PD. In the March 2010, edition of Nature Reviews Urology, it was again reported that these drugs counteract the development of PD like fibrotic plaque in rat models. Whether this extends to humans is unknown, but certainly given the lack of an effective alternative treatment, this seems like it is worth a shot.