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A number of readers have been advised by their urologists that Verapamil is an
effective first line non-surgical treatment and they have solicited my opinion as to be
extremely painful and he did not think he could stand the pain. I am not going to
advise anyone concerning medical treatment. Since I had Verapamil injections, I can
provide some background and give you my own experience. My commentary is in
italics.

An article in the June 2007 issue of Urology offers some promise with Verapamil
injections, but also highlights the lack of solid data about our condition. In one study,
Dr. John Mulhall and colleagues at the Weil Medical College of Cornell University
injected Verapamil into the penile plaque of 94 men with Peyronies disease.
Verapamil is a drug used to treat high blood pressure and it relaxes the blood
vessels, increasing the supply of blood and oxygen. The average patient age was
44 years old and average duration of the disease at the time of treatment was 5.7
months. Six injections were given at two week intervals. Five months after treatment
18% had improvements in penile curvature, 60% were the same and 22% were
worse. Based on Mulhall’s database, this was a significant improvement compared
to other patients in his database. The study also demonstrated the safety of the
procedure. According to Dr. Mulhall, “Nobody knows exactly how the treatment
actually works. It is possible that the needle or saline that the Verapamil is in are just
as important as the drug.”

The last statement is truly amazing. It would be relatively simple to have a control
group injected with saline to see if there was a similar outcome? This just
emphasizes how little is known and how little is being done about our condition.
Also, it would be helpful if Dr. Mulhall mentioned how many people are in his
database.

My experience with Verapamil injections:  The procedure is performed by a
physician and a nurse. The base of the penis was swabbed with alcohol and for
some reasons I found this very creepy. I couldn’t look, but felt a sharp, burning,
stinging sensation when the Lidocain (numbing agent) was injected. After that it
was not that bad, it’s more unpleasant and uncomfortable than painful. Eight
injections were given deep into the penis which was not very pleasant, but
bearable. Immediately after the nurse applied pressure with his finger to stop any
bleeding and wrapped the penis tightly in gauze with instructions to remove it after
one hour. After each treatment, the next one was less frightening. One aspect that
was particularly unpleasant was to look at your penis after the treatment.  My last
treatment was a particularly aggressive treatment; my dick looked like a raspberry
for a week.

I have read a number of accounts where patients complained of post treatment
bleeding and a great deal of swelling. It’s extremely important to have a nurse or
physician’s assistant there to apply pressure and the gauze so this does not
happen.  Also, make sure your physician performs this treatment on a regular
basis. Urologists who do this once in a while are not who you want to perform this
procedure. The standard procedure is six treatments. If more is suggested, it may
be time to find another urologist.

Did this treatment help? Who knows? But I would do it again. There really is no
other non surgical treatment opinion.